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Chemotherapy and endocrine therapy appear consistently associated with crci in patients with breast cancer, primarily affecting memory, attention/concentration, executive functioning, and processing speed. Cross sectional studies indicate patients treated with chemotherapy have more gray matter and white matter volume loss than controls, reduced white matter integrity, and altered brain activation.to conclude. Janelsins mc, heckler ce, peppone lj, et al
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An analysis from a nationwide, multicenter, prospective longitudinal study. Bc patients before their chemotherapy treatment, bc patients 3 ~ 9 months after the completion of chemotherapy, and noncancer controls. Breast cancer survivors who received chemotherapy plus endocrine therapy had statistically significant and clinically meaningful change in perceived cognitive impairment at 3 and 6 months, compared with those who received endocrine therapy alone, but this difference abated over time.
In this multicenter trial, patients were randomized to receive adjuvant endocrine therapy concurrent with, or sequential to, radiotherapy.
We compared subjective and objective neuropsychological performances among three groups of people
