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Main pages @natalee.007 @agnts.007 @natalee_muses Natalee was a positive study of kisqali efficacy and safety in the broadest range of patients at risk of recurrence, including those with no nodal involvement Observed adverse events remained stable.
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What is the natalee trial For years, natalee’s disappearance remained an agonizing mystery, sparking widespread media coverage, endless speculation, and tireless efforts by her family to uncover the truth The natalee trial is a large, global, randomized study evaluating the addition of ribociclib to standard endocrine therapy (nsai ± goserelin in premenopausal women) in hr+/her2− early breast cancer.
Compared to the monarche (3) trial, natalee study enrolled a wider population, including patients with anatomical stage ii and those without lymph node involvement (n0)
Therefore, it is reasonable to use stage ii and iii as stratification factors in randomization stratification strategy. The natalee trial is evaluating the efficacy and safety of ribociclib plus standard adjuvant et versus standard adjuvant et alone.