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Neurodegenerative disorders in humans may be triggered or exacerbated by exposure to occupational or environmental agents H410 very toxic to aquatic life with long lasting effects Here, we show that a brief exposure to methylisothiazolinone, a widely used industrial and household biocide, is highly toxic.
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Ewg’s skin deep rates thousands of personal care product ingredients, culled from ingredient labels on products, based on hazard information pulled from the scientific literature and industry, academic and regulatory databases. H317 may cause an allergic skin reaction The researchers stated, “a brief exposure to methylisothiazolinone, a widely used industrial and household biocide, is highly toxic to cultured neurons….” the scientists went on to state that these toxic effects had been reported previously, and because of their widespread use, the consequences of chronic human exposure need to be evaluated.
In evaluating pesticides for complete set of studies from pesticide and environmental effects of each mitigation measures or regulatory pesticide's risks
Epa then reregisters posing unreasonable risks to human when a pesticide is eligible for its decision in a reregistration sheet summarizes the information in 3092, methylisothiazolinone Methylisothiazolinone at 97.5% was slightly toxic in rats in an acute dermal toxicity study.3 the substance was corrosive to the skin The ld50 was calculated to be 242 mg/kg body weight. Methylisothiazolinone (mit) and methylchloroisothiazolinone (cmit) may be hard to pronounce, but they can be even harder on the body
These common preservatives are found in many liquid personal care products, and have been linked to lung toxicity,[1] allergic reactions, and possible neurotoxicity.[2] While it does serve the practical purpose of preserving products by preventing microbial growth, the adverse effects on both skin health and neurological function make its overall impact negative Methylisothiazolinone hazard statements h301+h311 toxic if swallowed or in contact with skin H314 causes severe skin burns and eye damage
